Description
| Product Name: | ZEB1 Polyclonal Antibody |
| Product Code: | CAB22244 |
| Reactivity: | Human, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, Jurkat, Rat heart |
| Cellular Location: | cytosol, nucleoplasm, nucleus |
This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 800-900 of human ZEB1 (NP_110378.3). |
| Sequence: | INIAI PTVTA QLPTI VAIAD QNSVP CLRAL AANKQ TILIP QVAYT YSTTV SPAVQ EPPLK VIQPN GNQDE RQDTS SEGVS NVEDQ NDSDS TPPKK KMRKT E |
| Synonyms: | BZP, TCF8, AREB6, FECD6, NIL2A, PPCD3, ZFHEP, ZFHX1A, DELTAEF1 |
| Calculated MW: | 124kDa |
| Observed MW: | 200kDa |