ZC3H13 Antibody (PACO22692)
- SKU:
- PACO22692
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ZC3H13 Antibody (PACO22692) |
| Antibody SKU: | PACO22692 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from internal of human ZC3H13. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from HepG2 cells, A549 cells and Jurkat cells, using ZC3H13 antibody. |
| Background: | 2 isoforms of the human protein are produced by alternative splicing. |
| Synonyms: | ZC313; |
| UniProt Protein Function: | Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing (PubMed:29507755). Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs at the 3'-UTR (). Controls embryonic stem cells (ESCs) pluripotency via its role in m6A methylation (). In the WMM complex, anchors component of the MACOM subcomplex in the nucleus (). Also required for bridging WTAP to the RNA-binding component RBM15 (RBM15 or RBM15B) (). |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q5T200 |
| NCBI GenInfo Identifier: | 1060099184 |
| NCBI Gene ID: | 23091 |
| NCBI Accession: | NP_001070256.1 |
| UniProt Secondary Accession: | Q5T200,O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6, A2A323 |
| UniProt Related Accession: | Q5T200 |
| Molecular Weight: | 200 KD |
| NCBI Full Name: | zinc finger CCCH domain-containing protein 13 isoform 1 |
| NCBI Synonym Full Names: | zinc finger CCCH-type containing 13 |
| NCBI Official Symbol: | ZC3H13 |
| NCBI Official Synonym Symbols: | Xio; KIAA0853 |
| NCBI Protein Information: | zinc finger CCCH domain-containing protein 13 |
| UniProt Protein Name: | Zinc finger CCCH domain-containing protein 13 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Zinc finger CCCH domain-containing protein |
| UniProt Gene Name: | ZC3H13 |
| UniProt Entry Name: |
| Antibodies |
| ZC3H13 Antibody (PACO01719) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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