ZBTB32 Antibody (PACO42854)
- SKU:
- PACO42854
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ZBTB32 Antibody (PACO42854) |
| Antibody SKU: | PACO42854 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Zinc finger and BTB domain-containing protein 32 protein (1-294AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: ZBTB32 antibody at 4µg/ml. Lane 1: Mouse brain tissue. Lane 2: Jurkat whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 53 kDa. Observed band size: 53 kDa. |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO42854 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO42854 at dilution of 1:100. |
| Background: | DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells (By similarity). |
| Synonyms: | Zinc finger and BTB domain-containing protein 32 (FANCC-interacting protein) (Fanconi anemia zinc finger protein) (Testis zinc finger protein) (Zinc finger protein 538), ZBTB32, FAZF TZFP ZNF538 |
| UniProt Protein Function: | ZBTB32: DNA-binding protein that binds to the to a 5'- TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells. Belongs to the krueppel C2H2-type zinc-finger protein family.Protein type: DNA-binding; C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 19q13.1Cellular Component: nucleoplasm; nucleusMolecular Function: DNA binding; protein binding; transcription corepressor activity; zinc ion bindingBiological Process: DNA damage response, detection of DNA damage; negative regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9Y2Y4 |
| NCBI GenInfo Identifier: | 74762048 |
| NCBI Gene ID: | 27033 |
| NCBI Accession: | Q9Y2Y4.1 |
| UniProt Secondary Accession: | Q9Y2Y4,Q8WVP2 |
| UniProt Related Accession: | Q9Y2Y4 |
| Molecular Weight: | 52,963 Da |
| NCBI Full Name: | Zinc finger and BTB domain-containing protein 32 |
| NCBI Synonym Full Names: | zinc finger and BTB domain containing 32 |
| NCBI Official Symbol: | ZBTB32 |
| NCBI Official Synonym Symbols: | Rog; FAXF; FAZF; TZFP; ZNF538 |
| NCBI Protein Information: | zinc finger and BTB domain-containing protein 32 |
| UniProt Protein Name: | Zinc finger and BTB domain-containing protein 32 |
| UniProt Synonym Protein Names: | FANCC-interacting protein; Fanconi anemia zinc finger protein; Testis zinc finger protein; Zinc finger protein 538 |
| Protein Family: | Zinc finger and BTB domain-containing protein |
| UniProt Gene Name: | ZBTB32 |
| UniProt Entry Name: | ZBT32_HUMAN |
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