| UniProt Protein Function: | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. |
| NCBI Summary: | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008] |
| UniProt Code: | P63104 |
| NCBI GenInfo Identifier: | 52000887 |
| NCBI Gene ID: | 7534 |
| NCBI Accession: | P63104.1 |
| UniProt Secondary Accession: | P63104,P29213, P29312, Q32P43, Q5XJ08, Q6GPI2, Q6IN74 Q6NUR9, Q6P3U9, Q86V33, A8K1N0, B7Z465, |
| UniProt Related Accession: | P63104 |
| Molecular Weight: | 19,333 Da |
| NCBI Full Name: | 14-3-3 protein zeta/delta |
| NCBI Synonym Full Names: | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta |
| NCBI Official Symbol: | YWHAZ |
| NCBI Official Synonym Symbols: | HEL4; YWHAD; KCIP-1; HEL-S-3; HEL-S-93; 14-3-3-zeta |
| NCBI Protein Information: | 14-3-3 protein zeta/delta |
| UniProt Protein Name: | 14-3-3 protein zeta/delta |
| UniProt Synonym Protein Names: | Protein kinase C inhibitor protein 1; KCIP-1 |
| Protein Family: | 14-3-3 protein |
| UniProt Gene Name: | YWHAZ |
