Description
Product Name: | YTHDF1 Monoclonal Antibody |
Product Code: | CAB23773 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC59730 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | Jurkat, NIH/3T3, C6 |
Cellular Location: | Cytoplasm |
Enables N6-methyladenosine-containing RNA binding activity and ribosome binding activity. Involved in mRNA destabilization; positive regulation of translational initiation; and stress granule assembly. Located in P-body and cytoplasmic stress granule.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240aa of human YTHDF1 (NP_060268.2). |
Sequence: | MSATS VDTQR TKGQD NKVQN GSLHQ KDTVH DNDFE PYLTG QSNQS NSYPS MSDPY LSSYY PPSIG FPYSL NEAPW STAGD PPIPY LTTYG QLSNG DHHFM HDAVF GQPGG LGNNI YQHRF NFFPE NPAFS AWGTS GSQGQ QTQSS AYGSS YTYPP SSLGG TVVDG QPGFH SDTLS KAPGM NSLEQ GMVGL KIGDV SSSAV KTVGS VVSSV ALTGV LSGNG GTNVN MPVSK PTSWA AIASK |
Synonyms: | YTHDF1, C20orf21, YTH domain-containing family protein 1 |
Calculated MW: | 20kDa/60kDa |
Observed MW: | 70kDa |