Description
Product Name: | YTHDC1 Monoclonal Antibody |
Product Code: | CAB22992 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC59465 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, IP, ELISA |
Key Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:500-1:1000, IP 1:1000, -1:5000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | K-562, U-87MG |
Cellular Location: | Nucleus |
Enables N6-methyladenosine-containing RNA binding activity. Involved in mRNA export from nucleus; mRNA splice site selection; and regulation of gene expression. Located in nuclear speck and plasma membrane.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-71 of human YTHDC1 (NP_001026902.1). |
Sequence: | MAADS REEKD GELNV LDDIL TEVPE QDDEL YNPES EQDKN EKKGS KRKSD RMEST DTKRQ KPSVH SRQLV S |
Synonyms: | YT521, YT521-B |
Calculated MW: | 85kDa |
Observed MW: | 110kDa |