Microbiology Recombinant Proteins

Yeast GLRX1 Recombinant Protein (RPPB1699)

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SKU:
RPPB1699
Product Type:
Recombinant Protein
Species:
Yeast
Uniprot:
P25373
Research Area:
Microbiology

Description

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Product Name:Yeast GLRX1 Recombinant Protein
Product Code:RPPB1699
Size:50µg
Species:Yeast
Target:GLRX1
Synonyms:Thioltransferase, GRX, GLRX1, GRX1, GRX-1, GLRX-1, Glutathione-dependent oxidoreductase 1, Glutaredoxin 1.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear colorless solution.
Formulation:Glutaredoxin solution contains 25mM Tris-HCl pH-7.5 & 0.01% Na Azide.
Stability:1 week at 2-10°C. For long term store at -20 to -80°C.
Purity:Greater than 90% as determined by SDS-PAGE.
UniProt Code:P25373

GLRX1 has a glutathione-disulfide oxidoreductase activity in the presence of nadph and glutathione reductase. reduces low molecular weight disulfides and proteins.Glutaredoxin is a glutathione (GSH)-dependent hydrogen donor for ribonucleotide reductase and also catalyzes glutathione-disulfide oxidoreduction reactions in the presence of NADPH and glutathione reductase. GLRX1 is multifunctional enzyme with glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase (GST) activity. The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing cytosolic protein- and non-protein-disulfides in a coupled system with glutathione reductase. Required for resistance to reactive oxygen species (ROS) by directly reducing hydroperoxides and for the detoxification of ROS-mediated damage.

Glutaredoxin Saccharamyces cerevisiae Recombinant containing 6x His tag at C-Terminus produced in E.Coli is a single, non-glycosylated, Polypeptide chain having a molecular mass of 16 kDa.

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