Yap1 Polyclonal Antibody (CAB24501)
- SKU:
- CAB24501
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | Yap1 Polyclonal Antibody |
| Product Code: | CAB24501 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:100-1:500, IF/ICC 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa |
This gene encodes a protein which binds to the SH3 domain of the Yes proto-oncogene product, a tyrosine kinase. This protein contains a WW domain, consisting of four conserved aromatic amino acids including two tryptophan residues. This conserved WW domain is found in various structural, regulatory and signaling molecules in various species, and may play a role in protein-protein interaction. Following cellular damage, phosphorylation of this encoded protein may suppress apoptosis. This protein may be involved in malignant transformation in cancer. Alternative splicing results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 139-488 of mouse Yap1 (NP_001164618.1). |
| Sequence: | APAAQ HLRQS SFEIP DDVPL PAGWE MAKTS SGQRY FLNHN DQTTT WQDPR KAMLS QLNVP APASP AVPQT LMNSA SGPLP DGWEQ AMTQD GEVYY INHKN KTTSW LDPRL DPRFA MNQRI TQSAP VKQPP PLAPQ SPQGG VLGGG SSNQQ QQIQL QQLQM EKERL RLKQQ ELFRQ AIRNI NPSTA NAPKC QELAL RSQLP TLEQD GGTPN AVSSP GMSQE LRTMT TNSSD PFLNS GTYHS RDEST DSGLS MSSYS IPRTP DDFLN SVDEM DTGDT ISQST LPSQQ SRFPD YLEAL PGTNV DLGTL EGDAM NIEGE ELMPS LQEAL SSEIL DVESV LAATK LDKES FLTWL |
| Synonyms: | Yap, Yki, Yap65, Yorkie |
| Calculated MW: | 52kDa |
| Observed MW: | 76kDa |
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