YAP1 Monoclonal Antibody (CAB22650)
- SKU:
- CAB22650
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IP
Description
| Product Name: | YAP1 Monoclonal Antibody |
| Product Code: | CAB22650 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC53469 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IP, ChIP, ELISA, CUT&Tag |
| Key Applications: | Western blotting, Immunoprecipitation |
| Recommended Dilution: | WB 1:2000-1:20000, IP 1:50-1:200, CUT&Tag 10, ⁵ cells /1 μgCHIP 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, Mouse heart, C6 |
| Cellular Location: | Cytoplasm, Nucleus |
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 155-504 of human YAP1(NP_001123617.1). |
| Sequence: | PTAQH LRQSS FEIPD DVPLP AGWEM AKTSS GQRYF LNHID QTTTW QDPRK AMLSQ MNVTA PTSPP VQQNM MNSAS GPLPD GWEQA MTQDG EIYYI NHKNK TTSWL DPRLD PRFAM NQRIS QSAPV KQPPP LAPQS PQGGV MGGSN SNQQQ QMRLQ QLQME KERLR LKQQE LLRQA MRNIN PSTAN SPKCQ ELALR SQLPT LEQDG GTQNP VSSPG MSQEL RTMTT NSSDP FLNSG TYHSR DESTD SGLSM SSYSV PRTPD DFLNS VDEMD TGDTI NQSTL PSQQN RFPDY LEAIP GTNVD LGTLE GDGMN IEGEE LMPSL QEALS SDILN DMESV LAATK LDKES FLTWL |
| Synonyms: | YAP, YKI, COB1, YAP2, YAP-1, YAP65 |
| Calculated MW: | 54kDa |
| Observed MW: | 70kDa |
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