XYLT1 Antibody (PACO13270)
- SKU:
- PACO13270
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | XYLT1 Antibody (PACO13270) |
| Antibody SKU: | PACO13270 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human XYLT1 |
| Form: | Liquid |
| Storage Buffer: | 0.1M NaHCO3,0.1M Glycine, 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | xylosyltransferase I;XYLT1;XT-I;XT1 ; |
| UniProt Protein Function: | XYLT1: Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes. Belongs to the glycosyltransferase 14 family. XylT subfamily.Protein type: Glycan Metabolism - heparan sulfate biosynthesis; Transferase; EC 2.4.2.26; Membrane protein, integral; Glycan Metabolism - chondroitin sulfate biosynthesisChromosomal Location of Human Ortholog: 16p12.3Cellular Component: Golgi membraneMolecular Function: protein xylosyltransferase activityBiological Process: glycosaminoglycan biosynthetic processDisease: Desbuquois Dysplasia 2; Pseudoxanthoma Elasticum |
| UniProt Protein Details: | |
| NCBI Summary: | This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum.[provided by RefSeq, Nov 2009] |
| UniProt Code: | Q86Y38 |
| NCBI GenInfo Identifier: | 71164803 |
| NCBI Gene ID: | 64131 |
| NCBI Accession: | Q86Y38.1 |
| UniProt Secondary Accession: | Q86Y38,Q9H1B6 |
| UniProt Related Accession: | Q86Y38 |
| Molecular Weight: | 107,569 Da |
| NCBI Full Name: | Xylosyltransferase 1 |
| NCBI Synonym Full Names: | xylosyltransferase 1 |
| NCBI Official Symbol: | XYLT1 |
| NCBI Official Synonym Symbols: | XT1; XTI; XT-I; DBQD2; XYLTI; PXYLT1; xylT-I |
| NCBI Protein Information: | xylosyltransferase 1 |
| UniProt Protein Name: | Xylosyltransferase 1 |
| UniProt Synonym Protein Names: | Peptide O-xylosyltransferase 1; Xylosyltransferase I; XT-I; XylT-I |
| Protein Family: | Xylosyltransferase |
| UniProt Gene Name: | XYLT1 |
| UniProt Entry Name: | XYLT1_HUMAN |
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