Description
Product Name: | XPO6 Polyclonal Antibody |
Product Code: | CAB24463 |
Reactivity: | Human, Mouse |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | 293F, HeLa, OVCAR-3, Mouse testis, Mouse thymus |
Cellular Location: | Cytoplasm, Nucleus |
The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 116-216 of human XPO6 (NP_055986.1). |
Sequence: | DIGRQ DWPMF YHDFF TNILQ LIQSP VTTPL GLIML KTTSE ELACP REDLS VARKE ELRKL LLDQV QTVLG LLTGI LETVW DKHSV TAATP PPSPT SGESG D |
Synonyms: | XPO6, EXP6, RANBP20, exportin-6 |
Calculated MW: | 127kDa/128kDa |
Observed MW: | 128kDa |