XIRP2 Antibody (PACO58044)
- SKU:
- PACO58044
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | XIRP2 Antibody (PACO58044) |
| Antibody SKU: | PACO58044 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Xin actin-binding repeat-containing protein 2 protein (2861-3004AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO58044 diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | IHC image of PACO58044 diluted at 1:300 and staining in paraffin-embedded human skeletal muscle tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Protects actin filaments from depolymerization. |
| Synonyms: | Xin actin-binding repeat-containing protein 2 (Beta-xin) (Cardiomyopathy-associated protein 3) (Xeplin), XIRP2, CMYA3 |
| UniProt Protein Function: | CMYA3: Protects actin filaments from depolymerization. Belongs to the Xin family. 7 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 2q24.3Cellular Component: cell junction; Z discMolecular Function: actin binding; alpha-actinin bindingBiological Process: intercellular junction assembly and maintenance; cardiac muscle morphogensis; actin cytoskeleton organization and biogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | A4UGR9 |
| NCBI GenInfo Identifier: | 119372315 |
| NCBI Gene ID: | 129446 |
| NCBI Accession: | NP_001073278.1 |
| UniProt Secondary Accession: | A4UGR9,Q53R52, Q5MJ67, Q702N7, Q86T36, Q86T38, A0PJ94 B2BBS0, B2BBS1, B2BBS4 |
| UniProt Related Accession: | A4UGR9 |
| Molecular Weight: | 382,300 Da |
| NCBI Full Name: | xin actin-binding repeat-containing protein 2 isoform 2 |
| NCBI Synonym Full Names: | xin actin-binding repeat containing 2 |
| NCBI Official Symbol: | XIRP2 |
| NCBI Official Synonym Symbols: | CMYA3 |
| NCBI Protein Information: | xin actin-binding repeat-containing protein 2; xeplin; beta-xin; myomaxin; xin repeat protein 2; cardiomyopathy associated 3; cardiomyopathy-associated protein 3 |
| UniProt Protein Name: | Xin actin-binding repeat-containing protein 2 |
| UniProt Synonym Protein Names: | Beta-xin; Cardiomyopathy-associated protein 3; Xeplin |
| Protein Family: | Xin actin-binding repeat-containing protein |
| UniProt Gene Name: | XIRP2 |
| UniProt Entry Name: | XIRP2_HUMAN |
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