Description
Product Name: | WTAP Polyclonal Antibody |
Product Code: | CAB22004 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunofluorescence |
Recommended Dilution: | WB 1:100-1:500, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | RAW264.7 |
Cellular Location: | cytoplasm, nuclear membrane, nuclear speck, nucleoplasm, nucleus |
The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in several transcript variants encoding three different isoforms.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 212-355 of human WTAP (NP_004897.2). |
Sequence: | DEEVE GMQST ILVLQ QQLKE TRQQL AQYQQ QQSQA SAPST SRTTA SEPVE QSEAT SKDCS RLTNG PSNGS SSRQR TSGSG FHREG NTTED DFPSS PGNGN KSSNS SEERT GRGGS GYVNQ LSAGY ESVDS PTGSE NSLTH QSND |
Synonyms: | Mum2 |
Calculated MW: | 44kDa |
Observed MW: | 55kDa |