WTAP Monoclonal Antibody
- SKU:
- CAB22751
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | WTAP Monoclonal Antibody |
| Product Code: | CAB22751 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC56272 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:10000-1:50000, IHC-P 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, RAW 264.7, Rat thymus |
| Cellular Location: | Nucleus, Nucleus speckle, nucleoplasm |
The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in several transcript variants encoding three different isoforms.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 212-355 of human WTAP(NP_004897.2). |
| Sequence: | DEEVE GMQST ILVLQ QQLKE TRQQL AQYQQ QQSQA SAPST SRTTA SEPVE QSEAT SKDCS RLTNG PSNGS SSRQR TSGSG FHREG NTTED DFPSS PGNGN KSSNS SEERT GRGGS GYVNQ LSAGY ESVDS PTGSE NSLT |
| Synonyms: | Mum2 |
| Calculated MW: | 44kDa |
| Observed MW: | 60kDa |
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