WNT8A Antibody (PACO20919)
- SKU:
- PACO20919
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | WNT8A Antibody (PACO20919) |
| Antibody SKU: | PACO20919 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human WNT8A |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20919(WNT8A Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and may be implicated in development of early embryos as well as germ cell tumors. Multiple alternatively spliced transcript variants have been found for this gene. |
| Synonyms: | wingless-type MMTV integration site family, member 8A |
| UniProt Protein Function: | WNT8A: Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus. Belongs to the Wnt family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted; Secreted, signal peptide; Extracellular matrixChromosomal Location of Human Ortholog: 5q31Cellular Component: extracellular space; proteinaceous extracellular matrix; extracellular regionMolecular Function: frizzled binding; receptor agonist activityBiological Process: neuron differentiation; response to retinoic acid; neural crest cell fate commitment; palate development; Wnt receptor signaling pathway through beta-catenin |
| UniProt Protein Details: | |
| NCBI Summary: | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and may be implicated in development of early embryos as well as germ cell tumors. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2014] |
| UniProt Code: | Q9H1J5 |
| NCBI GenInfo Identifier: | 14495176 |
| NCBI Gene ID: | 7478 |
| NCBI Accession: | BAB60960.1 |
| UniProt Secondary Accession: | Q9H1J5,Q96S51 |
| UniProt Related Accession: | Q9H1J5 |
| Molecular Weight: | 39,527 Da |
| NCBI Full Name: | WNT8A |
| NCBI Synonym Full Names: | wingless-type MMTV integration site family, member 8A |
| NCBI Official Symbol: | WNT8A |
| NCBI Official Synonym Symbols: | WNT8D |
| NCBI Protein Information: | protein Wnt-8a; WNT8d; protein Wnt-8d |
| UniProt Protein Name: | Protein Wnt-8a |
| UniProt Synonym Protein Names: | Protein Wnt-8d |
| Protein Family: | Protein |
| UniProt Gene Name: | WNT8A |
| UniProt Entry Name: | WNT8A_HUMAN |
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