Description
| Antibody Name: | WEE2 Antibody (PACO13751) |
| Antibody SKU: | PACO13751 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Human WEE2 |
| Form: | Liquid |
| Storage Buffer: | 0.1M NaHCO3,0.1M Glycine, 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | WEE1 homolog 2 (S. pombe);WEE2;FLJ16107;WEE1B ; |
| UniProt Protein Function: | WEE1B: a protein kinase of the WEE family expressed only in oocytes. Downregulation by RNAi causes a leaky meiotic arrest. The inhibitory effects of the kinase are enhanced when Ser15 is phosphorylated. Appears to be a key MPF inhibitory kinase in mouse oocytes and is required for maintaining meiotic arrest.Protein type: Protein kinase, Other; EC 2.7.10.2; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Other group; WEE family; WEE1 subfamilyChromosomal Location of Human Ortholog: 7q32Cellular Component: nucleoplasm; cytoplasmMolecular Function: protein serine/threonine kinase activity; magnesium ion binding; non-membrane spanning protein tyrosine kinase activity; ATP bindingBiological Process: mitosis; peptidyl-tyrosine phosphorylation; female pronucleus formation; negative regulation of cyclin-dependent protein kinase activity; female meiosis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P0C1S8 |
| NCBI GenInfo Identifier: | 157738687 |
| NCBI Gene ID: | 494551 |
| NCBI Accession: | NP_001099028.1 |
| UniProt Secondary Accession: | P0C1S8 |
| UniProt Related Accession: | P0C1S8 |
| Molecular Weight: | 62,925 Da |
| NCBI Full Name: | wee1-like protein kinase 2 |
| NCBI Synonym Full Names: | WEE1 homolog 2 (S. pombe) |
| NCBI Official Symbol: | WEE2 |
| NCBI Official Synonym Symbols: | WEE1B |
| NCBI Protein Information: | wee1-like protein kinase 2; wee1B kinase; wee1-like protein kinase 1B |
| UniProt Protein Name: | Wee1-like protein kinase 2 |
| UniProt Synonym Protein Names: | Wee1-like protein kinase 1B; Wee1B kinase |
| Protein Family: | Wee1-like protein kinase |
| UniProt Gene Name: | WEE2 |
| UniProt Entry Name: | WEE2_HUMAN |