Description
| Product Name: | WEE1 Monoclonal Antibody |
| Product Code: | CAB22275 |
| Reactivity: | Mouse |
| Applications: | Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC57004 |
| Reactivity: | Mouse |
| Tested Applications: | IHC-P, ELISA |
| Key Applications: | Immunohistochemistry |
| Recommended Dilution: | IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Cellular Location: | cytoplasm, nucleolus, nucleoplasm, nucleus |
This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human WEE1 (NP_003381.1). |
| Sequence: | MSFLS RQQPP PPRRA GAACT LRQKL IFSPC SDCEE EEEEE EEEGS GHSTG EDSAF QEPDS PLPPA RSPTE PGPER RRSPG PAPGS PGELE EDLLL PGACP |
| Synonyms: | WEE1A, WEE1hu |
| Calculated MW: | 72kDa |
| Observed MW: | Refer to figures |