Description
Product Name: | WEE1 Monoclonal Antibody |
Product Code: | CAB22275 |
Reactivity: | Mouse |
Applications: | Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC57004 |
Reactivity: | Mouse |
Tested Applications: | IHC-P, ELISA |
Key Applications: | Immunohistochemistry |
Recommended Dilution: | IHC-P 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Cellular Location: | cytoplasm, nucleolus, nucleoplasm, nucleus |
This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human WEE1 (NP_003381.1). |
Sequence: | MSFLS RQQPP PPRRA GAACT LRQKL IFSPC SDCEE EEEEE EEEGS GHSTG EDSAF QEPDS PLPPA RSPTE PGPER RRSPG PAPGS PGELE EDLLL PGACP |
Synonyms: | WEE1A, WEE1hu |
Calculated MW: | 72kDa |
Observed MW: | Refer to figures |