WDR74 Antibody (PACO36846)
- SKU:
- PACO36846
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | WDR74 Antibody (PACO36846) |
| Antibody SKU: | PACO36846 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human WD repeat-containing protein 74 protein (111-366AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: WDR74 antibody at 0.5µg/ml + Hela whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 43, 41 kDa. Observed band size: 43 kDa. |
 | Immunohistochemistry of paraffin-embedded human liver tissue using PACO36846 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO36846 at dilution of 1:100. |
| Background: | Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit. Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL. Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development (By similarity). |
| Synonyms: | WD repeat-containing protein 74 (NOP seven-associated protein 1), WDR74, NSA1 |
| UniProt Protein Function: | WDR74: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Nucleolus; Unknown functionChromosomal Location of Human Ortholog: 11q12.3Cellular Component: nucleolus; nucleusBiological Process: RNA metabolic process; blastocyst formation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6RFH5 |
| NCBI GenInfo Identifier: | 55976441 |
| NCBI Gene ID: | 54663 |
| NCBI Accession: | Q6RFH5.1 |
| UniProt Secondary Accession: | Q6RFH5,Q9BRC9, Q9H6X8, Q9NVY2, A8K8G5 |
| UniProt Related Accession: | Q6RFH5 |
| Molecular Weight: | 40,208 Da |
| NCBI Full Name: | WD repeat-containing protein 74 |
| NCBI Synonym Full Names: | WD repeat domain 74 |
| NCBI Official Symbol: | WDR74 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | WD repeat-containing protein 74; NOP seven-associated protein 1 |
| UniProt Protein Name: | WD repeat-containing protein 74 |
| UniProt Synonym Protein Names: | NOP seven-associated protein 1 |
| Protein Family: | WD repeat-containing protein |
| UniProt Gene Name: | WDR74 |
| UniProt Entry Name: | WDR74_HUMAN |
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