WDR62 Antibody (PACO31080)
- SKU:
- PACO31080
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | WDR62 Antibody (PACO31080) |
| Antibody SKU: | PACO31080 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human WD repeat-containing protein 62 protein (889-1188AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human bladder cancer using PACO31080 at dilution of 1:100. |
| Background: | Required for cerebral cortical development. Plays a role in neuronal proliferation and migration. Plays a role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and CEP63 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. |
| Synonyms: | WD repeat-containing protein 62, WDR62, C19orf14 |
| UniProt Protein Function: | Required for cerebral cortical development. Plays a role in neuronal proliferation and migration (PubMed:20890278, PubMed:20729831). Plays a role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and CEP63 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (PubMed:26297806). |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is proposed to play a role in cerebral cortical development. Mutations in this gene have been associated with microencephaly, cortical malformations, and mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011] |
| UniProt Code: | O43379 |
| NCBI GenInfo Identifier: | 145580608 |
| NCBI Gene ID: | 284403 |
| NCBI Accession: | NP_001077430.1 |
| UniProt Secondary Accession: | O43379,Q63HP9, Q659D7, Q8NBF7, Q96AD9 |
| UniProt Related Accession: | O43379 |
| Molecular Weight: | 166,511 Da |
| NCBI Full Name: | WD repeat-containing protein 62 isoform 1 |
| NCBI Synonym Full Names: | WD repeat domain 62 |
| NCBI Official Symbol: | WDR62 |
| NCBI Official Synonym Symbols: | MCPH2; C19orf14 |
| NCBI Protein Information: | WD repeat-containing protein 62 |
| UniProt Protein Name: | WD repeat-containing protein 62 |
| UniProt Synonym Protein Names: | |
| Protein Family: | WD repeat-containing protein |
| UniProt Gene Name: | WDR62 |
| UniProt Entry Name: | WDR62_HUMAN |
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