WDR36 Antibody (PACO20878)
- SKU:
- PACO20878
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | WDR36 Antibody (PACO20878) |
| Antibody SKU: | PACO20878 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:20-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human WDR36 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20878(WDR36 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20878(WDR36 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acid, typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG). |
| Synonyms: | WD repeat domain 36 |
| UniProt Protein Function: | WDR36: Involved in T-cell activation and highly co-regulated with IL2. Defects in WDR36 are the cause of primary open angle glaucoma type 1G (GLC1G). Primary open angle glaucoma (POAG) is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. The disease is asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place. |
| UniProt Protein Details: | Protein type:Nucleolus Chromosomal Location of Human Ortholog: 5q22.1 Cellular Component: small subunit processome; nucleolus Biological Process: retinal homeostasis; visual perception; response to stimulus; regulation of axon extension; rRNA processing Disease: Glaucoma 1, Open Angle, G |
| NCBI Summary: | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG). [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8NI36 |
| NCBI GenInfo Identifier: | 21281677 |
| NCBI Gene ID: | 134430 |
| NCBI Accession: | NP_644810.1 |
| UniProt Secondary Accession: | Q8NI36,Q68E02, Q8N1Q2, A2RUS4, |
| UniProt Related Accession: | Q8NI36 |
| Molecular Weight: | 105kd |
| NCBI Full Name: | WD repeat-containing protein 36 |
| NCBI Synonym Full Names: | WD repeat domain 36 |
| NCBI Official Symbol: | WDR36 |
| NCBI Official Synonym Symbols: | GLC1G; UTP21; TAWDRP; TA-WDRP |
| NCBI Protein Information: | WD repeat-containing protein 36 |
| UniProt Protein Name: | WD repeat-containing protein 36 |
| UniProt Synonym Protein Names: | T-cell activation WD repeat-containing protein; TA-WDRP |
| Protein Family: | WD repeat-containing protein |
| UniProt Gene Name: | WDR36 |
| UniProt Entry Name: | WDR36_HUMAN |
| Antibodies |
| Anti-WDR36 Antibody (CAB15566) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
SIM1 Antibody
Overview Product Name:SIM1 AntibodyProduct Code:PACO64949Size:50µLTarget Names:SIM1Species Reactivity:HumanHost
eutC Antibody
Overview Product Name:eutC AntibodyProduct Code:PACO64709Size:50µLTarget Names:eutCSpecies Reactivity:Escherichia coli
EPHA10 Antibody
Overview Product Name:EPHA10 AntibodyProduct Code:PACO64693Size:50µLTarget Names:EPHA10Species Reactivity:HumanH