Description
Product Name: | VSNL1/VILIP-1 Monoclonal Antibody |
Product Code: | CAB22101 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC54745 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunofluorescence |
Recommended Dilution: | WB 1:1000-1:5000, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | SH-SY5Y, Mouse lung, Rat lung |
Cellular Location: | cytosol |
This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2-191 of human VSNL1/VILIP-1 (NP_003376.2). |
Sequence: | GKQNS KLAPE VMEDL VKSTE FNEHE LKQWY KGFLK DCPSG RLNLE EFQQL YVKFF PYGDA SKFAQ HAFRT FDKNG DGTID FREFI CALSI TSRGS FEQKL NWAFN MYDLD GDGKI TRVEM LEIIE AIYKM VGTVI MMKMN EDGLT PEQRV DKIFS KMDKN KDDQI TLDEF KEAAK SDPSI VLLLQ CDIQK |
Synonyms: | HLP3, VILIP, HPCAL3, HUVISL1, VILIP-1 |
Calculated MW: | 22kDa |
Observed MW: | 18kDa |