VSIG4 Antibody (PACO51250)
- SKU:
- PACO51250
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | VSIG4 Antibody (PACO51250) |
| Antibody SKU: | PACO51250 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human V-set and immunoglobulin domain-containing protein 4 protein (20-283AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human lung tissue using PACO51250 at dilution of 1:100. |
 | Immunofluorescent analysis of A549 cells using PACO51250 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases. |
| Synonyms: | V-set and immunoglobulin domain-containing protein 4 (Protein Z39Ig), VSIG4, CRIg Z39IG |
| UniProt Protein Function: | VSIG4: Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Receptor, misc.Chromosomal Location of Human Ortholog: Xq12-q13.3 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
| UniProt Code: | Q9Y279 |
| NCBI GenInfo Identifier: | 59799152 |
| NCBI Gene ID: | 11326 |
| NCBI Accession: | Q9Y279.1 |
| UniProt Secondary Accession: | Q9Y279,Q6UXI4 |
| UniProt Related Accession: | Q9Y279 |
| Molecular Weight: | 33,857 Da |
| NCBI Full Name: | V-set and immunoglobulin domain-containing protein 4 |
| NCBI Synonym Full Names: | V-set and immunoglobulin domain containing 4 |
| NCBI Official Symbol: | VSIG4 |
| NCBI Official Synonym Symbols: | CRIg; Z39IG |
| NCBI Protein Information: | V-set and immunoglobulin domain-containing protein 4 |
| UniProt Protein Name: | V-set and immunoglobulin domain-containing protein 4 |
| UniProt Synonym Protein Names: | Protein Z39Ig |
| Protein Family: | V-set and immunoglobulin domain-containing protein |
| UniProt Gene Name: | VSIG4 |
| UniProt Entry Name: | VSIG4_HUMAN |
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