VPS53 Antibody (PACO17431)
- SKU:
- PACO17431
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | VPS53 Antibody (PACO17431) |
| Antibody SKU: | PACO17431 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human VPS53 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: A172 cell, Primary antibody: PACO17431(VPS53 Antibody) at dilution 1/200 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO17431(VPS53 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | This gene encodes a protein with sequence similarity to the yeast Vps53p protein. Vps53p is involved in retrograde vesicle trafficking in late Golgi. May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid, hydrolases such as CTSD. |
| Synonyms: | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein with sequence similarity to the yeast Vps53p protein. Vps53p is involved in retrograde vesicle trafficking in late Golgi. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q5VIR6 |
| NCBI GenInfo Identifier: | 13543951 |
| NCBI Gene ID: | 55275 |
| NCBI Accession: | BC006116 |
| UniProt Secondary Accession: | Q5VIR6,Q8WYW3, Q9BRR2, Q9BY02, Q9NV25, A8K2S8, B3FH42 |
| UniProt Related Accession: | Q5VIR6 |
| Molecular Weight: | 94,405 Da |
| NCBI Full Name: | Homo sapiens vacuolar protein sorting 53 homolog (S. cerevisiae), mRNA |
| NCBI Synonym Full Names: | VPS53, GARP complex subunit |
| NCBI Official Symbol: | VPS53 |
| NCBI Official Synonym Symbols: | HCCS1; PCH2E; hVps53L; pp13624 |
| NCBI Protein Information: | vacuolar protein sorting-associated protein 53 homolog |
| UniProt Protein Name: | |
| UniProt Synonym Protein Names: | |
| Protein Family: | Vacuolar protein sorting-associated protein |
| UniProt Gene Name: | |
| UniProt Entry Name: |
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