VPS52 Antibody (PACO13198)
- SKU:
- PACO13198
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | VPS52 Antibody (PACO13198) |
| Antibody SKU: | PACO13198 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human VPS52 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | vacuolar protein sorting 52 homolog (S. cerevisiae);VPS52;ARE1;DKFZp547I194;RP5-1033B10;SAC2;SACM2L;dJ1033B10.5 ; |
| UniProt Protein Function: | VPS52: May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Belongs to the VPS52 family.Chromosomal Location of Human Ortholog: 6p21.3Cellular Component: Golgi apparatus; membrane; perinuclear region of cytoplasm; recycling endosome; trans-Golgi network membraneMolecular Function: protein binding; syntaxin bindingBiological Process: endocytic recycling; lysosomal transport |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein that is similar to the yeast suppressor of actin mutations 2 gene. The yeast protein forms a subunit of the tetrameric Golgi-associated retrograde protein complex that is involved in vesicle trafficking from from both early and late endosomes, back to the trans-Golgi network. This gene is located on chromosome 6 in a head-to-head orientation with the gene encoding ribosomal protein S18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
| UniProt Code: | Q8N1B4 |
| NCBI GenInfo Identifier: | 74750887 |
| NCBI Gene ID: | 6293 |
| NCBI Accession: | Q8N1B4.1 |
| UniProt Secondary Accession: | Q8N1B4,Q53GR4, Q5JPA0, Q5SQW1, Q8IUN6, Q9NPT5, A2BF38 B0UZZ4, B4DNI9 |
| UniProt Related Accession: | Q8N1B4 |
| Molecular Weight: | 68,496 Da |
| NCBI Full Name: | Vacuolar protein sorting-associated protein 52 homolog |
| NCBI Synonym Full Names: | VPS52, GARP complex subunit |
| NCBI Official Symbol: | VPS52 |
| NCBI Official Synonym Symbols: | ARE1; SAC2; SACM2L; dJ1033B10.5 |
| NCBI Protein Information: | vacuolar protein sorting-associated protein 52 homolog |
| UniProt Protein Name: | Vacuolar protein sorting-associated protein 52 homolog |
| UniProt Synonym Protein Names: | SAC2 suppressor of actin mutations 2-like protein |
| Protein Family: | Vacuolar protein sorting-associated protein |
| UniProt Gene Name: | VPS52 |
| UniProt Entry Name: | VPS52_HUMAN |
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