VPS50 Antibody (PACO40154)
- SKU:
- PACO40154
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | VPS50 Antibody (PACO40154) |
| Antibody SKU: | PACO40154 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Syndetin protein (1-250AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human melanoma using PACO40154 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human brain tissue using PACO40154 at dilution of 1:100. |
| Background: | Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane. Within the EARP complex, required to tether the complex to recycling endosomes. Not involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). |
| Synonyms: | Syndetin (Coiled-coil domain-containing protein 132) (EARP/GARPII complex subunit VPS50), VPS50, CCDC132 KIAA1861 |
| UniProt Protein Function: | CCDC132: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 7q21.3Cellular Component: membrane; recycling endosomeMolecular Function: SNARE bindingBiological Process: endocytic recycling; retrograde transport, endosome to Golgi |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96JG6 |
| NCBI GenInfo Identifier: | 160019079 |
| NCBI Gene ID: | 55610 |
| NCBI Accession: | Q96JG6.3 |
| UniProt Secondary Accession: | Q96JG6,Q75N07, Q8WVK3, Q9H5C6, B3KX22, D1MQ00, F5H5U7 |
| UniProt Related Accession: | Q96JG6 |
| Molecular Weight: | 107,923 Da |
| NCBI Full Name: | Syndetin |
| NCBI Synonym Full Names: | VPS50, EARP/GARPII complex subunit |
| NCBI Official Symbol: | VPS50 |
| NCBI Official Synonym Symbols: | VPS54L; CCDC132 |
| NCBI Protein Information: | syndetin |
| UniProt Protein Name: | Syndetin |
| UniProt Synonym Protein Names: | Coiled-coil domain-containing protein 132 |
| Protein Family: | |
| UniProt Gene Name: | VPS50 |
| UniProt Entry Name: | VPS50_HUMAN |
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