VPS37D Antibody (PACO17446)
- SKU:
- PACO17446
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | VPS37D Antibody (PACO17446) |
| Antibody SKU: | PACO17446 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human VPS37D |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO17446(VPS37D Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17446(VPS37D Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. |
| Synonyms: | vacuolar protein sorting 37 homolog D (S. cerevisiae) |
| UniProt Protein Function: | VPS37D: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. VPS37D is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Belongs to the VPS37 family.Chromosomal Location of Human Ortholog: 7q11.23Cellular Component: endosome membraneBiological Process: autophagy; endosome transport; viral infectious cycle |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q86XT2 |
| NCBI GenInfo Identifier: | 117938318 |
| NCBI Gene ID: | 155382 |
| NCBI Accession: | |
| UniProt Secondary Accession: | Q86XT2,Q6P2C3 |
| UniProt Related Accession: | Q86XT2 |
| Molecular Weight: | 27,730 Da |
| NCBI Full Name: | vacuolar protein sorting-associated protein 37D |
| NCBI Synonym Full Names: | VPS37D, ESCRT-I subunit |
| NCBI Official Symbol: | VPS37D |
| NCBI Official Synonym Symbols: | WBSCR24 |
| NCBI Protein Information: | vacuolar protein sorting-associated protein 37D |
| UniProt Protein Name: | Vacuolar protein sorting-associated protein 37D |
| UniProt Synonym Protein Names: | ESCRT-I complex subunit VPS37D; Williams-Beuren syndrome chromosomal region 24 protein |
| Protein Family: | Vacuolar protein sorting-associated protein |
| UniProt Gene Name: | VPS37D |
| UniProt Entry Name: | VP37D_HUMAN |
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