VPS33A Antibody (PACO13192)
- SKU:
- PACO13192
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | VPS33A Antibody (PACO13192) |
| Antibody SKU: | PACO13192 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human VPS33A |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | vacuolar protein sorting 33 homolog A (S. cerevisiae);VPS33A;FLJ22395;FLJ23187 ; |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a tethering protein and a core subunit of the homotypic fusion and protein sorting (HOPS) complex. The HOPS complex and a second endosomal tethering complex called the class C core vacuole/endosome tethering (CORVET) complex, perform diverse functions in endocytosis including membrane tethering, RabGTPase interaction, activation and proofreading of synaptic-soluble N-ethylmaleimide-sensitive factor attachment receptor (SNARE) assembly to drive membrane fusion, and endosome-to-cytoskeleton attachment. The HOPS complex controls endosome maturation as well as endosome traffic to the lysosome. This complex is essential for vacuolar fusion and is required for adaptor protein complex 3-dependent transport from the golgi to the vacuole. The encoded protein belongs to the Sec1/Munc18 (SM) family of SNARE-mediated membrane fusion regulators. Naturally occurring mutations in this gene are associated with a novel mucopolysaccharidosis-like disease. [provided by RefSeq, Apr 2017] |
| UniProt Code: | Q96AX1 |
| NCBI GenInfo Identifier: | 18105056 |
| NCBI Gene ID: | 65082 |
| NCBI Accession: | NP_075067 |
| UniProt Secondary Accession: | Q96AX1 |
| UniProt Related Accession: | Q96AX1 |
| Molecular Weight: | Observed: 68 kDaPredicted: 68 kDa |
| NCBI Full Name: | vacuolar protein sorting-associated protein 33A isoform 1 |
| NCBI Synonym Full Names: | VPS33A core subunit of CORVET and HOPS complexes |
| NCBI Official Symbol: | VPS33A |
| NCBI Official Synonym Symbols: | MPSPS |
| NCBI Protein Information: | vacuolar protein sorting-associated protein 33A |
| UniProt Protein Name: | Vacuolar protein sorting-associated protein 33A |
| UniProt Synonym Protein Names: | |
| Protein Family: | Vacuolar protein sorting-associated protein |
| UniProt Gene Name: | VPS33A |
| UniProt Entry Name: | VP33A_HUMAN |
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