VPREB3 Antibody (PACO42414)
- SKU:
- PACO42414
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | VPREB3 Antibody (PACO42414) |
| Antibody SKU: | PACO42414 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Pre-B lymphocyte protein 3 protein (21-122AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. |
| Synonyms: | Pre-B lymphocyte protein 3 (N27C7-2) (Protein VPreB3), VPREB3 |
| UniProt Protein Function: | VPREB3: Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. Belongs to the immunoglobulin superfamily.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 22q11.23|22q11Cellular Component: endoplasmic reticulum; extracellular spaceBiological Process: immune response; immunoglobulin production |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is the human ortholog of the mouse VpreB3 (8HS20) protein, is thought to be involved in B-cell maturation, and may play a role in assembly of the pre-B cell receptor (pre-BCR). While the role of this protein in B-cell development has not yet been elucidated, studies with the chicken ortholog of this protein have found that when overexpressed, this protein localizes to the endoplasmic reticulum. The mouse ortholog of this protein has been shown to associate with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. Expression of this gene has been observed in some lymphomas. [provided by RefSeq, Apr 2015] |
| UniProt Code: | Q9UKI3 |
| NCBI GenInfo Identifier: | 7019567 |
| NCBI Gene ID: | 29802 |
| NCBI Accession: | NP_037510.1 |
| UniProt Secondary Accession: | Q9UKI3,B2R587 |
| UniProt Related Accession: | Q9UKI3 |
| Molecular Weight: | 13,710 Da |
| NCBI Full Name: | pre-B lymphocyte protein 3 |
| NCBI Synonym Full Names: | pre-B lymphocyte 3 |
| NCBI Official Symbol: | VPREB3 |
| NCBI Official Synonym Symbols: | 8HS20; N27C7-2 |
| NCBI Protein Information: | pre-B lymphocyte protein 3 |
| UniProt Protein Name: | Pre-B lymphocyte protein 3 |
| UniProt Synonym Protein Names: | N27C7-2; Protein VPreB3 |
| Protein Family: | Pre-B lymphocyte protein |
| UniProt Gene Name: | VPREB3 |
| UniProt Entry Name: | VPRE3_HUMAN |
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