VOPP1 Antibody (PACO31708)
- SKU:
- PACO31708
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | VOPP1 Antibody (PACO31708) |
| Antibody SKU: | PACO31708 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Vesicular, overexpressed in cancer, prosurvival protein 1 protein (23-172AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: VOPP1 antibody at 2µg/ml Lane 1: EC109 whole cell lysate Lane 2: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/15000 dilution Predicted band size: 20, 19, 18 kDa Observed band size: 50 kDa . |
| Background: | Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed. |
| Synonyms: | Vesicular, overexpressed in cancer, prosurvival protein 1 (EGFR-coamplified and overexpressed protein) (ECop) (Glioblastoma-amplified secreted protein) (Putative NF-kappa-B-activating protein 055N), VOPP1, ECOP GASP |
| UniProt Protein Function: | ECOP: Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed. Belongs to the VOPP1/ECOP family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 7p11.2Cellular Component: cytoplasmic vesicle membrane; endosomeMolecular Function: signal transducer activity |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96AW1 |
| NCBI GenInfo Identifier: | 74760714 |
| NCBI Gene ID: | 81552 |
| NCBI Accession: | Q96AW1.1 |
| UniProt Secondary Accession: | Q96AW1,Q6FIE3, Q8NBN8, Q96RE5, Q9H0W4, B0AZU1, B2RAT4 B3KS72, C9JWR3 |
| UniProt Related Accession: | Q96AW1 |
| Molecular Weight: | 17,381 Da |
| NCBI Full Name: | Vesicular, overexpressed in cancer, prosurvival protein 1 |
| NCBI Synonym Full Names: | vesicular, overexpressed in cancer, prosurvival protein 1 |
| NCBI Official Symbol: | VOPP1 |
| NCBI Official Synonym Symbols: | ECOP; GASP |
| NCBI Protein Information: | vesicular, overexpressed in cancer, prosurvival protein 1 |
| UniProt Protein Name: | Vesicular, overexpressed in cancer, prosurvival protein 1 |
| UniProt Synonym Protein Names: | EGFR-coamplified and overexpressed protein; ECop; Glioblastoma-amplified secreted protein; Putative NF-kappa-B-activating protein 055N |
| Protein Family: | Vesicular, overexpressed in cancer, prosurvival protein |
| UniProt Gene Name: | VOPP1 |
| UniProt Entry Name: | VOPP1_HUMAN |
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