VKORC1L1 Antibody (PACO37906)
- SKU:
- PACO37906
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | VKORC1L1 Antibody (PACO37906) |
| Antibody SKU: | PACO37906 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Vitamin K epoxide reductase complex subunit 1-like protein 1 protein (38-91AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human pancreatic cancer using PACO37906 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human stomach tissue using PACO37906 at dilution of 1:100. |
| Background: | Involved in vitamin K metabolism. Can reduce inactive vitamin K 2,3-epoxide to active vitamin K (in vitro), and may contribute to vitamin K-mediated protection against oxidative stress. Plays a role in vitamin K-dependent gamma-carboxylation of Glu residues in target proteins. |
| Synonyms: | Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1-like protein 1) (EC 1.17.4.4), VKORC1L1 |
| UniProt Protein Function: | VKORC1L1: Belongs to the VKOR family.Protein type: EC 1.1.4.1; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 7q11.21Cellular Component: endoplasmic reticulum membraneMolecular Function: vitamin-K-epoxide reductase (warfarin-sensitive) activityBiological Process: peptidyl-glutamic acid carboxylation; vitamin K metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8N0U8 |
| NCBI GenInfo Identifier: | 62511214 |
| NCBI Gene ID: | 154807 |
| NCBI Accession: | Q8N0U8.2 |
| UniProt Secondary Accession: | Q8N0U8,Q6AHW9, Q6TEK6, B4E222, E7ETM5 |
| UniProt Related Accession: | Q8N0U8 |
| Molecular Weight: | 19,753 Da |
| NCBI Full Name: | Vitamin K epoxide reductase complex subunit 1-like protein 1 |
| NCBI Synonym Full Names: | vitamin K epoxide reductase complex subunit 1 like 1 |
| NCBI Official Symbol: | VKORC1L1 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | vitamin K epoxide reductase complex subunit 1-like protein 1 |
| UniProt Protein Name: | Vitamin K epoxide reductase complex subunit 1-like protein 1 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Vitamin K epoxide reductase complex subunit 1-like protein |
| UniProt Gene Name: | VKORC1L1 |
| UniProt Entry Name: | VKORL_HUMAN |
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