Description
Antibody Name: | VKORC1L1 Antibody (PACO37906) |
Antibody SKU: | PACO37906 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Vitamin K epoxide reductase complex subunit 1-like protein 1 protein (38-91AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human pancreatic cancer using PACO37906 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human stomach tissue using PACO37906 at dilution of 1:100. |
Background: | Involved in vitamin K metabolism. Can reduce inactive vitamin K 2,3-epoxide to active vitamin K (in vitro), and may contribute to vitamin K-mediated protection against oxidative stress. Plays a role in vitamin K-dependent gamma-carboxylation of Glu residues in target proteins. |
Synonyms: | Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1-like protein 1) (EC 1.17.4.4), VKORC1L1 |
UniProt Protein Function: | VKORC1L1: Belongs to the VKOR family.Protein type: EC 1.1.4.1; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 7q11.21Cellular Component: endoplasmic reticulum membraneMolecular Function: vitamin-K-epoxide reductase (warfarin-sensitive) activityBiological Process: peptidyl-glutamic acid carboxylation; vitamin K metabolic process |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q8N0U8 |
NCBI GenInfo Identifier: | 62511214 |
NCBI Gene ID: | 154807 |
NCBI Accession: | Q8N0U8.2 |
UniProt Secondary Accession: | Q8N0U8,Q6AHW9, Q6TEK6, B4E222, E7ETM5 |
UniProt Related Accession: | Q8N0U8 |
Molecular Weight: | 19,753 Da |
NCBI Full Name: | Vitamin K epoxide reductase complex subunit 1-like protein 1 |
NCBI Synonym Full Names: | vitamin K epoxide reductase complex subunit 1 like 1 |
NCBI Official Symbol: | VKORC1L1 |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | vitamin K epoxide reductase complex subunit 1-like protein 1 |
UniProt Protein Name: | Vitamin K epoxide reductase complex subunit 1-like protein 1 |
UniProt Synonym Protein Names: | |
Protein Family: | Vitamin K epoxide reductase complex subunit 1-like protein |
UniProt Gene Name: | VKORC1L1 |
UniProt Entry Name: | VKORL_HUMAN |