Visfatin Monoclonal Antibody [P4D5AT] (CPAB0065)
![Visfatin Monoclonal Antibody [P4D5AT] (CPAB0065)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58294/63476/visfatin-monoclonal-antibody-p4d5at-cpab0065__01061__79847.1706534961.jpg?c=1 "Visfatin Monoclonal Antibody [P4D5AT] (CPAB0065)")
- SKU:
- CPAB0065
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- P4D5AT
- Applications:
- WB
- Applications:
- ELISA
![Visfatin Monoclonal Antibody [P4D5AT] (CPAB0065)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58294/63476/visfatin-monoclonal-antibody-p4d5at-cpab0065__01061__79847.1706534961.jpg?c=1&imbypass=on "Visfatin Monoclonal Antibody [P4D5AT] (CPAB0065)")
Description
system_update_alt Datasheet
| Product Name: | Visfatin Antibody |
| Product Sku: | CPAB0065 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human Visfatin mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with Recombinant human Visfatin amino acids 1-491 purified from Ecoli. |
| Clone: | P4D5AT. |
| Reactivity: | Human |
| Applications: | Western Blot, ELISA |
| Purification Method: | Visfatin antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Isotype: | IgG1 |
| Background: | Excess adiposity is the most important risk in the development of insulin resistance and type 2 diabetes mellitus (T2DM). Adipose tissue produces several proteins (adipocytokines) such as leptin, adiponectin, resistin, tumor necrosis factor-α, and IL-6, that modulate insulin sensitivity and appear to play an important role in the pathogenesis of insulin resistance, diabetes, dyslipidemia, inflammation, and atherosclerosis. However, the mechanisms by which fat tissue induces insulin resistance and the role of adipocytokines in the pathogenesis of T2DM have not been well established. Visfatin, also known as pre-B cell colony-enhancing factor (PBEF), is a cytokine that is highly expressed in visceral fat and was originally isolated as a secreted factor that synergizes with IL-7 and stem cell factors to promote the growth of B cell precursors. Visfatin homologs have been identified in carp, invertebrate mollusks, and bacteria, as well as in vertebrates, including humans and the mouse. It h |
| Synonyms: | PBEF, Pre-B cell colony-enhancing factor, Nicotinamide phosphoribosyltransferase NAmPRTase, Nampt, MGC117256, DKFZP666B131, 1110035O14Rik. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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