VEGFR2/KDR/Flk-1/CD309 Polyclonal Antibody
- SKU:
- CAB24671
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | VEGFR2/KDR/Flk-1/CD309 Polyclonal Antibody |
| Product Code: | CAB24671 |
| Reactivity: | Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse lung |
| Cellular Location: | Cell membrane |
Enables growth factor binding activity and vascular endothelial growth factor-activated receptor activity. Involved in several processes, including circulatory system development; peptidyl-tyrosine autophosphorylation; and positive regulation of vasculogenesis. Acts upstream of or within several processes, including animal organ development; positive regulation of cell population proliferation; and vasculature development. Located in several cellular components, including cell junction; endosome; and external side of plasma membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; extraembryonic component; and genitourinary system. Human ortholog(s) of this gene implicated in several diseases, including adhesions of uterus; artery disease (multiple); gastrointestinal system cancer (multiple); macular degeneration (multiple); and pancreatic cancer (multiple). Orthologous to human KDR (kinase insert domain receptor).
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-762 of mouse VEGFR2/KDR/Flk-1/CD309(NP_034742.2). |
| Sequence: | ASVGL PGDFL HPPKL STQKD ILTIL ANTTL QITCR GQRDL DWLWP NAQRD SEERV LVTEC GGGDS IFCKT LTIPR VVGND TGAYK CSYRD VDIAS TVYVY VRDYR SPFIA SVSDQ HGIVY ITENK NKTVV IPCRG SISNL NVSLC ARYPE KRFVP DGNRI SWDSE IGFTL PSYMI SYAGM VFCEA KINDE TYQSI MYIVV VVGYR IYDVI LSPPH EIELS AGEKL VLNCT ARTEL NVGLD FTWHS PPSKS HHKKI VNRDV KPFPG TVAKM FLSTL TIESV TKSDQ GEYTC VASSG RMIKR NRTFV RVHTK PFIAF GSGMK SLVEA TVGSQ VRIPV KYLSY PAPDI KWYRN GRPIE SNYTM IVGDE LTIME VTERD AGNYT VILTN PISME KQSHM VSLVV NVPPQ IGEKA LISPM DSYQY GTMQT LTCTV YANPP LHHIQ WYWQL EEACS YRPGQ TSPYA CKEWR HVEDF QGGNK IEVTK NQYAL IEGKN KTVST LVIQA ANVSA LYKCE AINKA GRGER VISFH VIRGP EITVQ PAAQP TEQES VSLLC TADRN TFENL TWYKL GSQAT SVHMG ESLTP VCKNL DALWK LNGTM FSNST NDILI VAFQN ASLQD QGDYV CSAQD KKTKK RHCLV KQLII LERMA PMITG NLENQ TTTIG ETIEV TCPAS GNPTP HITWF KDNET LVEDS GIVLR DGNRN LTIRR VRKED GGLYT CQACN VLGCA RAETL FIIEG AQEKT NLE |
| Synonyms: | orv, Flk1, Ly73, Flk-1, Krd-1, VEGFR2, VEGFR-2, sVEGFR-2, 6130401C07 |
| Calculated MW: | 150kDa |
| Observed MW: | 230kDa |
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