VE Cadherin Monoclonal Antibody
- SKU:
- CAB22659
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | VE Cadherin Monoclonal Antibody |
| Product Code: | CAB22659 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC58056 |
| Reactivity: | Human |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | BEWO, |
| Cellular Location: | Cell junction, Cell membrane, Single-pass type I membrane protein |
This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 48-593 of human VE Cadherin (NP_001786.2) |
| Sequence: | DWIWN QMHID EEKNT SLPHH VGKIK SSVSR KNAKY LLKGE YVGKV FRVDA ETGDV FAIER LDREN ISEYH LTAVI VDKDT GENLE TPSSF TIKVH DVNDN WPVFT HRLFN ASVPE SSAVG TSVIS VTAVD ADDPT VGDHA SVMYQ ILKGK EYFAI DNSGR IITIT KSLDR EKQAR YEIVV EARDA QGLRG DSGTA TVLVT LQDIN DNFPF FTQTK YTFVV PEDTR VGTSV GSLFV EDPDE PQNRM TKYSI LRGDY QDAFT IETNP AHNEG IIKPM KPLDY EYIQQ YSFIV EATDP TIDLR YMSPP AGNRA QVIIN ITDVD EPPIF QQPFY HFQLK ENQKK PLIGT VLAMD PDAAR HSIGY SIRRT SDKGQ FFRVT KKGDI YNEKE LDREV YPWYN LTVEA KELDS TGTPT GKESI VQVHI EVLDE NDNAP EFAKP YQPKV CENAV HGQLV LQISA IDKDI TPRNV KFKFI LNTEN NFTLT DNHDN TANIT VKYGQ FDREH TKVHF LPVVI SDNGM PSRTG TSTLT VAVCK CNEQG EFTFC EDMAA Q |
| Synonyms: | 7B4, CD144 |
| Calculated MW: | 88kDa |
| Observed MW: | 90-140kDa |
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