Antibody Name:	VDAC1 Antibody (PACO62091)
Antibody SKU:	PACO62091
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:500-1:2000
Species Reactivity:	Arabidopsis thaliana
Immunogen:	Recombinant Arabidopsis thaliana Mitochondrial outer membrane protein porin 1 protein (2-276AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Western Blot. Positive WB detected in: Arabidopsis thaliana leaf tissue, Apium graveolens leaf tissue, Spinacia oleracea leaf tissue, Glycine max leaf tissue, Capsicum annuum leaf tissue, Solanum tuberosum leaf tissue, Vicia faba leaf tissue, Ipomoea batatas leaf tissue. All lanes: VDAC1 antibody at 1:1000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 30 kDa. Observed band size: 30 kDa.

Background:

Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity). Involved in plant development at reproductive stage, is important for pollen development and may regulate hydrogen peroxide generation during disease resistance.

Synonyms:

Mitochondrial outer membrane protein porin 1 (Voltage-dependent anion-selective channel protein 1) (AtVDAC1) (VDAC-1), VDAC1

UniProt Protein Function:	Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective (). Involved in plant development at reproductive stage, is important for pollen development and may regulate hydrogen peroxide generation during disease resistance.
UniProt Protein Details:
NCBI Summary:	Encodes a voltage-dependent anion channel (VDAC: AT3G01280/VDAC1, AT5G67500/VDAC2, AT5G15090/VDAC3, AT5G57490/VDAC4, AT5G15090/VDAC5). VDACs are reported to be porin-type, beta-barrel diffusion pores. They are prominently localized in the outer mitochondrial membrane and are involved in metabolite exchange between the organelle and the cytosol.
UniProt Code:	Q9SRH5
NCBI GenInfo Identifier:	15232074
NCBI Gene ID:	820914
NCBI Accession:	NP_186777.1
UniProt Secondary Accession:	Q9SRH5
UniProt Related Accession:	Q9SRH5
Molecular Weight:	Predicted Molecular Mass: 60.6kDaAccurate Molecular Mass: 61kDa as determined by SDS-PAGE reducing conditions.
NCBI Full Name:	voltage dependent anion channel 1
NCBI Synonym Full Names:
NCBI Official Symbol:	VDAC1
NCBI Official Synonym Symbols:	5076; ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 1; ATVDAC1; T22N4.9; T22N4_9; VDAC1; voltage dependent anion channel 1
NCBI Protein Information:	voltage dependent anion channel 1
UniProt Protein Name:	Mitochondrial outer membrane protein porin 1
UniProt Synonym Protein Names:	Voltage-dependent anion-selective channel protein 1; AtVDAC1; VDAC-1
Protein Family:	Voltage-dependent anion-selective channel protein
UniProt Gene Name:	VDAC1
UniProt Entry Name:	VDAC1_ARATH