VASH2 Antibody (PACO17415)
- SKU:
- PACO17415
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | VASH2 Antibody (PACO17415) |
| Antibody SKU: | PACO17415 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Full length fusion protein |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hela and 293T cell, Primary antibody: PACO17415(VASH2 Antibody) at dilution 1/450 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds. |
| Background: | Vasohibin-2, also known as VASH2, is a 355 amino acid, protein belonging to the Vasohibin family. Expressed in various embryonic organs, Vasohibin-2 can be detected during embryonic weeks six through twelve and is found in vessels of 20-week embryonic organs as well as in endothelial cells of neonatal large vessels. Induced by VEGF, Vasohibin-2 is an angiogenesis inhibitor and interferes with the proliferation, migration and network formation by endothelial cells. |
| Synonyms: | vasohibin 2 |
| UniProt Protein Function: | VASH2: Angiogenesis inhibitor. Inhibits network formation by endothelial cells. Belongs to the vasohibin family. 5 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 1q32.3Cellular Component: cytoplasmBiological Process: positive regulation of angiogenesis; positive regulation of endothelial cell proliferation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q86V25 |
| NCBI GenInfo Identifier: | 210147527 |
| NCBI Gene ID: | 79805 |
| NCBI Accession: | NP_001129947.1 |
| UniProt Secondary Accession: | Q86V25,Q2VT46, Q5VTE7, Q5VTE9, Q7Z6E3, Q8IZ24, Q9H9W5 |
| UniProt Related Accession: | Q86V25 |
| Molecular Weight: | 40,450 Da |
| NCBI Full Name: | vasohibin-2 isoform 3 |
| NCBI Synonym Full Names: | vasohibin 2 |
| NCBI Official Symbol: | VASH2 |
| NCBI Official Synonym Symbols: | RP11-275G3.1 |
| NCBI Protein Information: | vasohibin-2; vasohibin-like protein |
| UniProt Protein Name: | Vasohibin-2 |
| UniProt Synonym Protein Names: | Vasohibin-like protein |
| Protein Family: | Vasohibin |
| UniProt Gene Name: | VASH2 |
| UniProt Entry Name: | VASH2_HUMAN |
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