VAMP1/VAMP2/VAMP3 Antibody (PACO03098)
- SKU:
- PACO03098
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | VAMP1/VAMP2/VAMP3 Antibody |
| Antibody SKU: | PACO03098 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | IHC:1:100-1:300 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from the Internal region of human VAMP-1/2/3. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | VAMP1; SYB1; Vesicle-associated membrane protein 1; VAMP-1; Synaptobrevin-1; VAMP2; SYB2; Vesicle-associated membrane protein 2; VAMP-2; Synaptobrevin-2; VAMP3; SYB3; Vesicle-associated membrane protein 3; VAMP-3; Cellubrevin; CEB; Synaptob |
| UniProt Protein Function: | VAMP1: Involved in the targeting and/or fusion of transport vesicles to their target membrane. Belongs to the synaptobrevin family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 12p Cellular Component: cell junction; cell surface; cytosol; integral to plasma membrane; mitochondrial outer membrane; synaptic vesicle membrane; terminal button Molecular Function:protein binding; SNAP receptor activity; SNARE binding Biological Process: vesicle fusion Disease: Spastic Ataxia 1, Autosomal Dominant |
| NCBI Summary: | Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2014] |
| UniProt Code: | P23763 |
| NCBI GenInfo Identifier: | 135093 |
| NCBI Gene ID: | 6843 |
| NCBI Accession: | P23763.1 |
| UniProt Secondary Accession: | P23763,O75468, Q15857, Q6FG94, Q8IVC9, A8MVP3, D3DUR3 |
| UniProt Related Accession: | P23763 |
| Molecular Weight: | 12,658 Da |
| NCBI Full Name: | Vesicle-associated membrane protein 1 |
| NCBI Synonym Full Names: | vesicle associated membrane protein 1 |
| NCBI Official Symbol: | VAMP1 |
| NCBI Official Synonym Symbols: | SYB1; SPAX1; VAMP-1 |
| NCBI Protein Information: | vesicle-associated membrane protein 1 |
| UniProt Protein Name: | Vesicle-associated membrane protein 1 |
| UniProt Synonym Protein Names: | Synaptobrevin-1 |
| Protein Family: | Vesicle-associated membrane protein |
| UniProt Gene Name: | VAMP1 |
| UniProt Entry Name: | VAMP1_HUMAN |
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