UST Antibody (PACO60464)
- SKU:
- PACO60464
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | UST Antibody (PACO60464) |
| Antibody SKU: | PACO60464 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Uronyl 2-sulfotransferase protein (85-183AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO60464 diluted at 1:200 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Sulfotransferase that catalyzes the transfer of sulfate to the position 2 of uronyl residues. Has mainly activity toward iduronyl residues in dermatan sulfate, and weaker activity toward glucuronyl residues of chondroitin sulfate. Has no activity toward desulfated N-resulfated heparin. |
| Synonyms: | Uronyl 2-sulfotransferase (EC 2.8.2), UST, DS2ST |
| UniProt Protein Function: | UST: Sulfotransferase that catalyzes the transfer of sulfate to the position 2 of uronyl residues. Has mainly activity toward iduronyl residues in dermatan sulfate, and weaker activity toward glucuronyl residues of chondroitin sulfate. Has no activity toward desulfated N-resulfated heparin. Belongs to the sulfotransferase 3 family.Protein type: Transferase; EC 2.8.2.-; Membrane protein, integral; Glycan Metabolism - chondroitin sulfate biosynthesisChromosomal Location of Human Ortholog: 6q25.1Cellular Component: Golgi membraneMolecular Function: sulfotransferase activityBiological Process: dermatan sulfate biosynthetic process; protein amino acid sulfation |
| UniProt Protein Details: | |
| NCBI Summary: | Uronyl 2-sulfotransferase transfers sulfate to the 2-position of uronyl residues, such as iduronyl residues in dermatan sulfate and glucuronyl residues in chondroitin sulfate (Kobayashi et al., 1999 [PubMed 10187838]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9Y2C2 |
| NCBI GenInfo Identifier: | 68052988 |
| NCBI Gene ID: | 10090 |
| NCBI Accession: | Q9Y2C2.1 |
| UniProt Secondary Accession: | Q9Y2C2,B2RCX6 |
| UniProt Related Accession: | Q9Y2C2 |
| Molecular Weight: | 47,673 Da |
| NCBI Full Name: | Uronyl 2-sulfotransferase |
| NCBI Synonym Full Names: | uronyl 2-sulfotransferase |
| NCBI Official Symbol: | UST |
| NCBI Official Synonym Symbols: | 2OST |
| NCBI Protein Information: | uronyl 2-sulfotransferase |
| UniProt Protein Name: | Uronyl 2-sulfotransferase |
| UniProt Synonym Protein Names: | |
| Protein Family: | Uronyl 2-sulfotransferase |
| UniProt Gene Name: | UST |
| UniProt Entry Name: | UST_HUMAN |
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