Description
Antibody Name: | USP28 Antibody (PACO13127) |
Antibody SKU: | PACO13127 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human USP28 |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | ubiquitin specific peptidase 28;USP28;KIAA1515 ; |
UniProt Protein Function: | USP28: a peptidase of the C19 family. USP28 and FBXW7 regulate Myc protein stability in response to DNA damage. Two isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.4.19.12; Protease; Ubiquitin-specific protease Chromosomal Location of Human Ortholog: 11q23.2 Cellular Component: nuclear body; nucleoplasm; protein complex Molecular Function:protein binding; ubiquitin-specific protease activity Biological Process: cell proliferation; DNA damage checkpoint; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; protein deubiquitination; Ras protein signal transduction; regulation of protein stability; response to DNA damage stimulus; response to ionizing radiation |
NCBI Summary: | The protein encoded by this gene is a deubiquitinase involved in the DNA damage pathway and DNA damage-induced apoptosis. Overexpression of this gene is seen in several cancers. [provided by RefSeq, Oct 2016] |
UniProt Code: | Q96RU2 |
NCBI GenInfo Identifier: | 20140700 |
NCBI Gene ID: | 57646 |
NCBI Accession: | Q96RU2.1 |
UniProt Secondary Accession: | Q96RU2,Q6NZX9, Q9P213, B0YJC0, B0YJC1, |
UniProt Related Accession: | Q96RU2 |
Molecular Weight: | 122kDa |
NCBI Full Name: | Ubiquitin carboxyl-terminal hydrolase 28 |
NCBI Synonym Full Names: | ubiquitin specific peptidase 28 |
NCBI Official Symbol: | USP28 |
NCBI Protein Information: | ubiquitin carboxyl-terminal hydrolase 28 |
UniProt Protein Name: | Ubiquitin carboxyl-terminal hydrolase 28 |
UniProt Synonym Protein Names: | Deubiquitinating enzyme 28; Ubiquitin thioesterase 28; Ubiquitin-specific-processing protease 28 |
Protein Family: | Ubiquitin carboxyl-terminal hydrolase |
UniProt Gene Name: | USP28 |