Description
| Antibody Name: | UPRT Antibody (PACO38698) |
| Antibody SKU: | PACO38698 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Uracil phosphoribosyltransferase homolog protein (1-309AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human cervical cancer using PACO38698 at dilution of 1:100. |
| Background: | cytosol, uridine kinase activity, pyrimidine nucleobase metabolic process, pyrimidine nucleoside salvage |
| Synonyms: | Uracil phosphoribosyltransferase homolog, UPRT |
| UniProt Protein Function: | UPRT: an enzyme which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. [provided by RefSeq, Nov 2009]Protein type: EC 2.4.2.9; Transferase; Nucleotide Metabolism - pyrimidineChromosomal Location of Human Ortholog: Xq13.3Cellular Component: cytosolMolecular Function: protein binding; uridine kinase activityBiological Process: pyrimidine base metabolic process; pyrimidine nucleoside salvage |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. [provided by RefSeq, Nov 2009] |
| UniProt Code: | Q96BW1 |
| NCBI GenInfo Identifier: | 74751783 |
| NCBI Gene ID: | 139596 |
| NCBI Accession: | Q96BW1.1 |
| UniProt Secondary Accession: | Q96BW1,Q5JRL1, Q5JRL3, Q68DN0, Q96MW2 |
| UniProt Related Accession: | Q96BW1 |
| Molecular Weight: | 19,056 Da |
| NCBI Full Name: | Uracil phosphoribosyltransferase homolog |
| NCBI Synonym Full Names: | uracil phosphoribosyltransferase homolog |
| NCBI Official Symbol: | UPRT |
| NCBI Official Synonym Symbols: | UPP; FUR1 |
| NCBI Protein Information: | uracil phosphoribosyltransferase homolog |
| UniProt Protein Name: | Uracil phosphoribosyltransferase homolog |
| UniProt Synonym Protein Names: | |
| Protein Family: | Uracil phosphoribosyltransferase |
| UniProt Gene Name: | UPRT |
| UniProt Entry Name: | UPP_HUMAN |
