Description
Antibody Name: | UPRT Antibody (PACO38698) |
Antibody SKU: | PACO38698 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Uracil phosphoribosyltransferase homolog protein (1-309AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human cervical cancer using PACO38698 at dilution of 1:100. |
Background: | cytosol, uridine kinase activity, pyrimidine nucleobase metabolic process, pyrimidine nucleoside salvage |
Synonyms: | Uracil phosphoribosyltransferase homolog, UPRT |
UniProt Protein Function: | UPRT: an enzyme which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. [provided by RefSeq, Nov 2009]Protein type: EC 2.4.2.9; Transferase; Nucleotide Metabolism - pyrimidineChromosomal Location of Human Ortholog: Xq13.3Cellular Component: cytosolMolecular Function: protein binding; uridine kinase activityBiological Process: pyrimidine base metabolic process; pyrimidine nucleoside salvage |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. [provided by RefSeq, Nov 2009] |
UniProt Code: | Q96BW1 |
NCBI GenInfo Identifier: | 74751783 |
NCBI Gene ID: | 139596 |
NCBI Accession: | Q96BW1.1 |
UniProt Secondary Accession: | Q96BW1,Q5JRL1, Q5JRL3, Q68DN0, Q96MW2 |
UniProt Related Accession: | Q96BW1 |
Molecular Weight: | 19,056 Da |
NCBI Full Name: | Uracil phosphoribosyltransferase homolog |
NCBI Synonym Full Names: | uracil phosphoribosyltransferase homolog |
NCBI Official Symbol: | UPRT |
NCBI Official Synonym Symbols: | UPP; FUR1 |
NCBI Protein Information: | uracil phosphoribosyltransferase homolog |
UniProt Protein Name: | Uracil phosphoribosyltransferase homolog |
UniProt Synonym Protein Names: | |
Protein Family: | Uracil phosphoribosyltransferase |
UniProt Gene Name: | UPRT |
UniProt Entry Name: | UPP_HUMAN |