UPP2 Antibody (PACO31004)
- SKU:
- PACO31004
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | UPP2 Antibody (PACO31004) |
| Antibody SKU: | PACO31004 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Uridine phosphorylase 2 protein (1-317AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: UPP2 antibody at 4µg/ml Lane 1: Mouse kidney tissue Lane 2: Mouse brain tissue Lane 3: Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 36, 42 kDa Observed band size: 36 kDa . |
| Background: | Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates. |
| Synonyms: | Uridine phosphorylase 2 (UPase 2) (UrdPase 2) (EC 2.4.2.3), UPP2 |
| UniProt Protein Function: | UPP2: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates. Belongs to the PNP/UDP phosphorylase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nucleotide Metabolism - pyrimidine; Xenobiotic Metabolism - drug metabolism - other enzymes; Phosphorylase; Transferase; EC 2.4.2.3 Chromosomal Location of Human Ortholog: 2q24.1 Cellular Component: cytosol; type III intermediate filament Molecular Function:protein binding; uridine phosphorylase activity Biological Process: pyrimidine nucleoside catabolic process; pyrimidine nucleoside salvage |
| UniProt Code: | O95045 |
| NCBI GenInfo Identifier: | 37538021 |
| NCBI Gene ID: | 151531 |
| NCBI Accession: | O95045.1 |
| UniProt Secondary Accession: | O95045,B3KV87, |
| UniProt Related Accession: | O95045 |
| Molecular Weight: | 41,602 Da |
| NCBI Full Name: | Uridine phosphorylase 2 |
| NCBI Synonym Full Names: | uridine phosphorylase 2 |
| NCBI Official Symbol: | UPP2 |
| NCBI Official Synonym Symbols: | UP2; UPASE2; UDRPASE2 |
| NCBI Protein Information: | uridine phosphorylase 2 |
| UniProt Protein Name: | Uridine phosphorylase 2 |
| Protein Family: | Uridine phosphorylase |
| UniProt Gene Name: | UPP2 |
| UniProt Entry Name: | UPP2_HUMAN |
| ELISA Kits |
| Human UPP2 ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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