UPP2 Antibody (PACO20838)
- SKU:
- PACO20838
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | UPP2 Antibody (PACO20838) |
| Antibody SKU: | PACO20838 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:30-1:150 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human UPP2 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO20838(UPP2 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | Gel: 6%SDS-PAGE,Lysate: 40 μgPrimary antibody: PACO20838(UPP2 Antibody) at dilution 1/400 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 40 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20838(UPP2 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates. |
| Synonyms: | uridine phosphorylase 2 |
| UniProt Protein Function: | UPP2: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates. Belongs to the PNP/UDP phosphorylase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nucleotide Metabolism - pyrimidine; Xenobiotic Metabolism - drug metabolism - other enzymes; Phosphorylase; Transferase; EC 2.4.2.3 Chromosomal Location of Human Ortholog: 2q24.1 Cellular Component: cytosol; type III intermediate filament Molecular Function:protein binding; uridine phosphorylase activity Biological Process: pyrimidine nucleoside catabolic process; pyrimidine nucleoside salvage |
| UniProt Code: | O95045 |
| NCBI GenInfo Identifier: | 37538021 |
| NCBI Gene ID: | 151531 |
| NCBI Accession: | O95045.1 |
| UniProt Secondary Accession: | O95045,B3KV87, |
| UniProt Related Accession: | O95045 |
| Molecular Weight: | 41,602 Da |
| NCBI Full Name: | Uridine phosphorylase 2 |
| NCBI Synonym Full Names: | uridine phosphorylase 2 |
| NCBI Official Symbol: | UPP2 |
| NCBI Official Synonym Symbols: | UP2; UPASE2; UDRPASE2 |
| NCBI Protein Information: | uridine phosphorylase 2 |
| UniProt Protein Name: | Uridine phosphorylase 2 |
| Protein Family: | Uridine phosphorylase |
| UniProt Gene Name: | UPP2 |
| UniProt Entry Name: | UPP2_HUMAN |
| ELISA Kits |
| Human UPP2 ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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