UNC5D Antibody (PACO61013)
- SKU:
- PACO61013
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | UNC5D Antibody (PACO61013) |
| Antibody SKU: | PACO61013 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Netrin receptor UNC5D protein (90-212AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence staining of Hela cells with PACO61013 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Receptor for the netrin NTN4 that promotes neuronal cell survival (By similarity). Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (By similarity). May play a role in apoptosis in response to DNA damage. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell (By similarity). |
| Synonyms: | Netrin receptor UNC5D (Protein unc-5 homolog 4) (Protein unc-5 homolog D), UNC5D, KIAA1777 UNC5H4 |
| UniProt Code: | Q6UXZ4 |
| NCBI GenInfo Identifier: | 54036576 |
| NCBI Gene ID: | 137970 |
| NCBI Accession: | Q6UXZ4.1 |
| UniProt Secondary Accession: | Q6UXZ4,Q8WYP7, |
| UniProt Related Accession: | Q6UXZ4 |
| Molecular Weight: | 953 |
| NCBI Full Name: | Netrin receptor UNC5D |
| NCBI Synonym Full Names: | unc-5 homolog D (C. elegans) |
| NCBI Official Symbol: | UNC5D |
| NCBI Official Synonym Symbols: | Unc5h4; PRO34692 |
| NCBI Protein Information: | netrin receptor UNC5D; unc-5 homolog 4; netrin receptor Unc5h4; protein unc-5 homolog 4; protein unc-5 homolog D |
| UniProt Protein Name: | Netrin receptor UNC5D |
| UniProt Synonym Protein Names: | Protein unc-5 homolog 4; Protein unc-5 homolog D |
| Protein Family: | Netrin receptor |
| UniProt Gene Name: | UNC5D |
| UniProt Entry Name: | UNC5D_HUMAN |
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