Description
| Product Name: | ULBP1 Monoclonal Antibody |
| Product Code: | CAB21161 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC3064 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | K-562, Mouse thymus |
| Cellular Location: | Cell membrane, Endoplasmic reticulum, GPI-anchor, Lipid-anchor |
The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant protein of Human ULBP1. |
| Sequence: | Email for sequence |
| Synonyms: | N2DL-1, RAET1I, NKG2DL1 |
| Calculated MW: | 28kDa |
| Observed MW: | 36kDa |