Description
Antibody Name: | UL48 Antibody (PACO34658) |
Antibody SKU: | PACO34658 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Human herpesvirus 1 |
Immunogen: | Recombinant Human herpesvirus 1 Tegument protein VP16 protein (1-490AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | Transcriptional activator of immediate-early (IE) gene products (α genes). Acts as a key activator of lytic infection by initiating the lytic program through the assembly of the transcriptional regulatory VP16-induced complex composed of VP16 and two cellular factors, HCFC1 and POU2F 1. VP16-induced complex represents a regulatory switch: when it is on, it promotes IE-gene expression and thus lytic infection, and when it is off, it limits IE-gene transcription favoring latent infection. |
Synonyms: | Tegument protein VP16 (α trans-inducing protein) (Alpha-TIF) (ICP25) (Vmw65) |
UniProt Protein Function: | Transcriptional activator of immediate-early (IE) gene products (alpha genes). Acts as a key activator of lytic infection by initiating the lytic program through the assembly of the transcriptional regulatory VP16-induced complex composed of VP16 and two cellular factors, HCFC1 and POU2F 1. VP16-induced complex represents a regulatory switch: when it is on, it promotes IE-gene expression and thus lytic infection, and when it is off, it limits IE-gene transcription favoring latent infection (). |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | P04486 |
NCBI GenInfo Identifier: | 259016402 |
NCBI Gene ID: | |
NCBI Accession: | P04486.2 |
UniProt Secondary Accession: | P04486 |
UniProt Related Accession: | P04486 |
Molecular Weight: | 54,316 Da |
NCBI Full Name: | Tegument protein VP16 |
NCBI Synonym Full Names: | |
NCBI Official Symbol: | |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | |
UniProt Protein Name: | Tegument protein VP16 |
UniProt Synonym Protein Names: | Alpha trans-inducing protein; Alpha-TIF; ICP25; Vmw65 |
Protein Family: | Tegument protein |
UniProt Gene Name: | UL48 |
UniProt Entry Name: | VP16_HHV1F |