Description
| Antibody Name: | UL48 Antibody (PACO34658) |
| Antibody SKU: | PACO34658 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human herpesvirus 1 |
| Immunogen: | Recombinant Human herpesvirus 1 Tegument protein VP16 protein (1-490AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Transcriptional activator of immediate-early (IE) gene products (α genes). Acts as a key activator of lytic infection by initiating the lytic program through the assembly of the transcriptional regulatory VP16-induced complex composed of VP16 and two cellular factors, HCFC1 and POU2F 1. VP16-induced complex represents a regulatory switch: when it is on, it promotes IE-gene expression and thus lytic infection, and when it is off, it limits IE-gene transcription favoring latent infection. |
| Synonyms: | Tegument protein VP16 (α trans-inducing protein) (Alpha-TIF) (ICP25) (Vmw65) |
| UniProt Protein Function: | Transcriptional activator of immediate-early (IE) gene products (alpha genes). Acts as a key activator of lytic infection by initiating the lytic program through the assembly of the transcriptional regulatory VP16-induced complex composed of VP16 and two cellular factors, HCFC1 and POU2F 1. VP16-induced complex represents a regulatory switch: when it is on, it promotes IE-gene expression and thus lytic infection, and when it is off, it limits IE-gene transcription favoring latent infection (). |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P04486 |
| NCBI GenInfo Identifier: | 259016402 |
| NCBI Gene ID: | |
| NCBI Accession: | P04486.2 |
| UniProt Secondary Accession: | P04486 |
| UniProt Related Accession: | P04486 |
| Molecular Weight: | 54,316 Da |
| NCBI Full Name: | Tegument protein VP16 |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Tegument protein VP16 |
| UniProt Synonym Protein Names: | Alpha trans-inducing protein; Alpha-TIF; ICP25; Vmw65 |
| Protein Family: | Tegument protein |
| UniProt Gene Name: | UL48 |
| UniProt Entry Name: | VP16_HHV1F |