UHMK1 Antibody (PACO19248)
- SKU:
- PACO19248
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | UHMK1 Antibody (PACO19248) |
| Antibody SKU: | PACO19248 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic peptide of human UHMK1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: PACO19248(UHMK1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes. |
| Background: | The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants. |
| Synonyms: | U2AF homology motif (UHM) kinase 1 |
| UniProt Protein Function: | KIS: a unique kinase that possesses an RNP type RNA-recognition motif (RRM). A proline-directed kinase with a specificity different from the MAP kinases and CDKs. May be involved in trafficking and/or processing of RNA.Protein type: Kinase, protein; EC 2.7.11.1; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor); Other group; Other-Unique familyChromosomal Location of Human Ortholog: 1q23.3Cellular Component: axon; dendrite cytoplasm; nucleusMolecular Function: ATP binding; mRNA binding; protein binding; protein serine/threonine kinase activity; ribonucleoprotein binding; transferase activityBiological Process: cell cycle arrest; mRNA catabolic process, nonsense-mediated decay; neurite development; peptidyl-serine phosphorylation; positive regulation of translational initiation; protein amino acid autophosphorylation; regulation of alternative nuclear mRNA splicing, via spliceosome; regulation of protein export from nucleus |
| UniProt Protein Details: | |
| NCBI Summary: | The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
| UniProt Code: | Q8TAS1 |
| NCBI GenInfo Identifier: | 24211880 |
| NCBI Gene ID: | 127933 |
| NCBI Accession: | Q8TAS1.2 |
| UniProt Secondary Accession: | Q8TAS1,Q96C22, A0A0A6YYC2, A8K8K4, G3V1M1 |
| UniProt Related Accession: | Q8TAS1 |
| Molecular Weight: | 39,044 Da |
| NCBI Full Name: | Serine/threonine-protein kinase Kist |
| NCBI Synonym Full Names: | U2AF homology motif (UHM) kinase 1 |
| NCBI Official Symbol: | UHMK1 |
| NCBI Official Synonym Symbols: | KIS; KIST; P-CIP2 |
| NCBI Protein Information: | serine/threonine-protein kinase Kist |
| UniProt Protein Name: | Serine/threonine-protein kinase Kist |
| UniProt Synonym Protein Names: | Kinase interacting with stathmin; PAM COOH-terminal interactor protein 2; P-CIP2; U2AF homology motif kinase 1 |
| Protein Family: | Serine/threonine-protein kinase |
| UniProt Gene Name: | UHMK1 |
| UniProt Entry Name: | UHMK1_HUMAN |
| Antibodies |
| UHMK1 Antibody (PACO13086) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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