UGT2A3 Antibody (PACO37086)
- SKU:
- PACO37086
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | UGT2A3 Antibody (PACO37086) |
| Antibody SKU: | PACO37086 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human UDP-glucuronosyltransferase 2A3 protein (201-491AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO37086 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO37086 at dilution of 1:100. |
| Background: | UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid, to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. |
| Synonyms: | UDP-glucuronosyltransferase 2A3 (UDPGT 2A3) (EC 2.4.1.17), UGT2A3 |
| UniProt Protein Function: | UGT2A3: UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Belongs to the UDP-glycosyltransferase family.Protein type: Xenobiotic Metabolism - drug metabolism - other enzymes; Lipid Metabolism - androgen and estrogen; Membrane protein, integral; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450; Carbohydrate Metabolism - pentose and glucuronate interconversions; Cofactor and Vitamin Metabolism - retinol; Carbohydrate Metabolism - ascorbate and aldarate; Transferase; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; EC 2.4.1.17; Carbohydrate Metabolism - starch and sucroseChromosomal Location of Human Ortholog: 4q13.2Cellular Component: intracellular membrane-bound organelleMolecular Function: glucuronosyltransferase activityBiological Process: flavonoid biosynthetic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6UWM9 |
| NCBI GenInfo Identifier: | 296452855 |
| NCBI Gene ID: | 79799 |
| NCBI Accession: | Q6UWM9.2 |
| UniProt Secondary Accession: | Q6UWM9,Q9H6S4 |
| UniProt Related Accession: | Q6UWM9 |
| Molecular Weight: | 60,254 Da |
| NCBI Full Name: | UDP-glucuronosyltransferase 2A3 |
| NCBI Synonym Full Names: | UDP glucuronosyltransferase family 2 member A3 |
| NCBI Official Symbol: | UGT2A3 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | UDP-glucuronosyltransferase 2A3 |
| UniProt Protein Name: | UDP-glucuronosyltransferase 2A3 |
| UniProt Synonym Protein Names: | |
| Protein Family: | UDP-glucuronosyltransferase |
| UniProt Gene Name: | UGT2A3 |
| UniProt Entry Name: | UD2A3_HUMAN |
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