UGGT2 Antibody (PACO17363)
- SKU:
- PACO17363
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | UGGT2 Antibody (PACO17363) |
| Antibody SKU: | PACO17363 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Full length fusion protein |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO17363(UGGT2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER. |
| Synonyms: | UDP-glucose glycoprotein glucosyltransferase 2 |
| UniProt Protein Function: | Function: Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation By similarity.Cofactor: Calcium or manganese.Pathway: Protein modification; protein glycosylation.Subunit structure: Interacts with METTL23. Ref.8Subcellular location: Endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment Ref.5. Tissue specificity: Higher levels in kidney, pancreas, heart, and skeletal muscle. Ref.1Sequence similarities: Belongs to the glycosyltransferase 8 family.Caution: Has no enzymatic activity towards unfolded RNase B or thyroglobulin (Ref.1). |
| UniProt Protein Details: | |
| NCBI Summary: | UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.[supplied by OMIM, Oct 2009] |
| UniProt Code: | Q9NYU1 |
| NCBI GenInfo Identifier: | 311033544 |
| NCBI Gene ID: | 55757 |
| NCBI Accession: | Q9NYU1.4 |
| UniProt Secondary Accession: | Q9NYU1,Q08AD0, Q5JQR8, Q9UFC4 |
| UniProt Related Accession: | Q9NYU1 |
| Molecular Weight: | 174,735 Da |
| NCBI Full Name: | UDP-glucose:glycoprotein glucosyltransferase 2 |
| NCBI Synonym Full Names: | UDP-glucose glycoprotein glucosyltransferase 2 |
| NCBI Official Symbol: | UGGT2 |
| NCBI Official Synonym Symbols: | UGT2; HUGT2; UGCGL2 |
| NCBI Protein Information: | UDP-glucose:glycoprotein glucosyltransferase 2; UDP-Glc:glycoprotein glucosyltransferase 2; UDP--Glc:glycoprotein glucosyltransferase 2; UDP-glucose ceramide glucosyltransferase-like 1; UDP-glucose ceramide glucosyltransferase-like 2 |
| UniProt Protein Name: | UDP-glucose:glycoprotein glucosyltransferase 2 |
| UniProt Synonym Protein Names: | UDP--Glc:glycoprotein glucosyltransferase 2; UDP-glucose ceramide glucosyltransferase-like 1 |
| Protein Family: | UDP-glucose:glycoprotein glucosyltransferase |
| UniProt Gene Name: | UGGT2 |
| UniProt Entry Name: | UGGG2_HUMAN |
| Antibodies |
| UGGT2 Antibody (PACO13077) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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