Description
| Antibody Name: | UFSP2 Antibody (PACO13074) |
| Antibody SKU: | PACO13074 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human UFSP2 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | UFM1-specific peptidase 2;UFSP2;C4orf20;FLJ11200 ; |
| UniProt Protein Function: | UFSP2: Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, an ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins. Belongs to the peptidase C78 family.Protein type: Protease; EC 3.4.22.-Chromosomal Location of Human Ortholog: 4q35.1Cellular Component: endoplasmic reticulum; cytoplasm; nucleusMolecular Function: protein binding; thiolester hydrolase activityBiological Process: regulation of estrogen receptor signaling pathway; proteolysisDisease: Beukes Hip Dysplasia |
| UniProt Protein Details: | |
| NCBI Summary: | Like ubiquitin (see MIM 191339), ubiquitin-fold modifier-1 (UFM1; MIM 610553) must be processed by a protease before it can conjugate with its target proteins. UFSP2 is a thiol protease that specifically processes the C terminus of UFM1 (Kang et al., 2007 [PubMed 17182609]).[supplied by OMIM, Oct 2009] |
| UniProt Code: | Q9NUQ7 |
| NCBI GenInfo Identifier: | 227498137 |
| NCBI Gene ID: | 55325 |
| NCBI Accession: | NP_060829.2 |
| UniProt Secondary Accession: | Q9NUQ7,Q6IA77, Q96FS3 |
| UniProt Related Accession: | Q9NUQ7 |
| Molecular Weight: | 53,261 Da |
| NCBI Full Name: | ufm1-specific protease 2 |
| NCBI Synonym Full Names: | UFM1-specific peptidase 2 |
| NCBI Official Symbol: | UFSP2 |
| NCBI Official Synonym Symbols: | C4orf20 |
| NCBI Protein Information: | ufm1-specific protease 2 |
| UniProt Protein Name: | Ufm1-specific protease 2 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Ufm1-specific protease |
| UniProt Gene Name: | UFSP2 |
| UniProt Entry Name: | UFSP2_HUMAN |