UCK1 Antibody (PACO30972)
- SKU:
- PACO30972
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | UCK1 Antibody (PACO30972) |
| Antibody SKU: | PACO30972 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Uridine-cytidine kinase 1 protein (1-201AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO30972 at dilution of 1:100. |
| Background: | Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N(4)-anisoylcytidine. |
| Synonyms: | Uridine-cytidine kinase 1 (UCK 1) (EC 2.7.1.48) (Cytidine monophosphokinase 1) (Uridine monophosphokinase 1), UCK1, URK1 |
| UniProt Protein Function: | UCK1: Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4- thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)- benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5- methylcytidine, and N(4)-anisoylcytidine. Belongs to the uridine kinase family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Kinase, other; Nucleotide Metabolism - pyrimidine; Xenobiotic Metabolism - drug metabolism - other enzymes; EC 2.7.1.48Chromosomal Location of Human Ortholog: 9q34.13Cellular Component: cytosolMolecular Function: nucleoside kinase activity; uridine kinase activityBiological Process: pyrimidine base metabolic process; pyrimidine nucleoside salvage |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a uridine-cytidine kinase that catalyzes the phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP) but not the phosphorylation of deoxyribonucleosides or purine ribonucleosides. This enzyme can also phosphorylate uridine and cytidine analogs and uses both ATP and GTP as a phosphate donor. Alternative splicing results in multiple splice variants encoding distinct isoforms. [provided by RefSeq, May 2012] |
| UniProt Code: | Q9HA47 |
| NCBI GenInfo Identifier: | 20455360 |
| NCBI Gene ID: | 83549 |
| NCBI Accession: | Q9HA47.1 |
| UniProt Secondary Accession: | Q9HA47,Q5JT09, Q5JT10, Q5JT12, Q5JT13, Q6IA74, Q96BJ0 |
| UniProt Related Accession: | Q9HA47 |
| Molecular Weight: | 32,275 Da |
| NCBI Full Name: | Uridine-cytidine kinase 1 |
| NCBI Synonym Full Names: | uridine-cytidine kinase 1 |
| NCBI Official Symbol: | UCK1 |
| NCBI Official Synonym Symbols: | URK1 |
| NCBI Protein Information: | uridine-cytidine kinase 1 |
| UniProt Protein Name: | Uridine-cytidine kinase 1 |
| UniProt Synonym Protein Names: | Cytidine monophosphokinase 1; Uridine monophosphokinase 1 |
| Protein Family: | Uridine-cytidine kinase |
| UniProt Gene Name: | UCK1 |
| UniProt Entry Name: | UCK1_HUMAN |
| Antibodies |
| UCK1 Antibody (PACO13066) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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