UBXN2B Antibody (PACO35402)
- SKU:
- PACO35402
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | UBXN2B Antibody (PACO35402) |
| Antibody SKU: | PACO35402 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human UBX domain-containing protein 2B protein (2-250AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human lung tissue using PACO35402 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human melanoma using PACO35402 at dilution of 1:100. |
 | Immunofluorescent analysis of HepG2 cells using PACO35402 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. |
| Synonyms: | UBX domain-containing protein 2B (NSFL1 cofactor p37) (p97 cofactor p37), UBXN2B |
| UniProt Protein Function: | UBXN2B: Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. Belongs to the NSFL1C family.Protein type: Adaptor/scaffold; Endoplasmic reticulumChromosomal Location of Human Ortholog: 8q12.1Cellular Component: Golgi apparatus; endoplasmic reticulum; cytosol; nucleusMolecular Function: ubiquitin binding; protein phosphatase type 1 regulator activityBiological Process: proteasomal ubiquitin-dependent protein catabolic process; regulation of catalytic activity; nuclear envelope reassembly; Golgi organization and biogenesis; autophagic vacuole formation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q14CS0 |
| NCBI GenInfo Identifier: | 121946691 |
| NCBI Gene ID: | 137886 |
| NCBI Accession: | Q14CS0.1 |
| UniProt Secondary Accession: | Q14CS0,B3KWZ3 |
| UniProt Related Accession: | Q14CS0 |
| Molecular Weight: | 37,077 Da |
| NCBI Full Name: | UBX domain-containing protein 2B |
| NCBI Synonym Full Names: | UBX domain protein 2B |
| NCBI Official Symbol: | UBXN2B |
| NCBI Official Synonym Symbols: | p37 |
| NCBI Protein Information: | UBX domain-containing protein 2B; p97 cofactor p37; NSFL1 cofactor p37 |
| UniProt Protein Name: | UBX domain-containing protein 2B |
| UniProt Synonym Protein Names: | NSFL1 cofactor p37; p97 cofactor p37 |
| Protein Family: | UBX domain-containing protein |
| UniProt Gene Name: | UBXN2B |
| UniProt Entry Name: | UBX2B_HUMAN |
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